Cationic Bioactive Peptide from the Seeds of Benincasa hispida
نویسندگان
چکیده
منابع مشابه
Cationic Bioactive Peptide from the Seeds of Benincasa hispida
A designated bioactive peptide "Hispidalin" purified from the seeds of Benincasa hispida, which is a medicinal plant, belongs to Cucurbitaceae family. Purification was achieved by using a procedure consisting of extraction from potassium phosphate buffer followed by FPLC and HPLC steps. Based on amino acid residue, this peptide is amphipathic and basic with one net positive charge having isoele...
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OBJECTIVES The antiulcer activity of Benincasa hispida (Thunb.) Cogn. fruit was evaluated in rats against ethanol-induced gastric mucosal damage, pylorus ligated (PL) gastric ulcers, and cold restraint-stress (CRS)-induced gastric ulcer models. METHODS Petroleum ether and methanol extracts were administrated orally at the dose of 300 mg/kg, and omeprazole (reference standard) at the dose of 2...
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Received: September 13, 2017 Revised: January 22, 2018 Accepted: March 05, 2018 Abstract: Background: Herbals have been proven to be offering a wide number of medicinal uses and are having multiple benefits when considered as a complete system of medicine. Benincasa plant is rich in phytoconstituents, present almost in every part of the plant. Roots are the parts on which minimum work has been ...
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The methanol extract of wax gourd, the fruits of Benincasa hispida cogn.(Cucurbitaceae) was found to show no inhibition against three gram positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, and Bacillus subtilis and three gram negative bacteria Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia by cup-plate method whereas antifungal studies showed significant in...
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Neuroleptic activity of methanolic extract of Benincasa hispida was assessed using apomorphine induced cage climbing model and catalepsy test in mice. Methanolic extract showed significant reduction in apomorphine induced cage climbing activity at 600 mg/kg and catalepsy in mice .The phytochemical analysis of methanolic extract showed presence of phenolic compounds and triterpene saponins, whic...
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ژورنال
عنوان ژورنال: International Journal of Peptides
سال: 2014
ISSN: 1687-9767,1687-9775
DOI: 10.1155/2014/156060